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TNIK Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM48107
复制产品信息
  • 种属：H，M
  • 用途：WB，ELISA
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    TNIK Rabbit Polyclonal Antibody
  • 别名
    KIAA0551
  • 类别
    抗体产品
  • 基因名称
    TNIK
  • 蛋白名称
    TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
  • Clonality
    Polyclonal
  • 推荐应用
    WB,ELISA
  • 稀释度
    WB 1:500-2000, ELISA 1:5000-20000
  • 反应种属
    Human,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
  • Human Gene ID
    23043
  • Human Swissprot No.
    Q9UKE5
  • Mouse Swissprot No.
    P83510
  • 免疫原
    Synthesized peptide derived from human protein . at AA range: 350-430
  • 特异性
    TNIK Polyclonal Antibody detects endogenous levels of protein.
  • 预测分子量
    149kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function (Fu et al., 1999 [PubMed 10521462]).[supplied by OMIM, Mar 2008],
  • 组织表达
    Expressed ubiquitously. Highest levels observed in heart, brain and skeletal muscle. Expressed in normal colonic epithelia and colorectal cancer tissues.
  • 细胞定位
    Nucleus. Cytoplasm. Recycling endosome. Cytoplasm, cytoskeleton. Associated with recycling endosomes and the cytoskeletal fraction upon RAP2A overexpression.
  • 功能
    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in cytoskeletal regulation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with TRAF2 and NCK.,tissue specificity:Expressed ubiquitously. Highest levels observed in heart, brain and skeletal muscle.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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