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DNAJB9 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM65856
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  • 种属：H，M，R
  • 用途：WB
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    DNAJB9 Rabbit Polyclonal Antibody
  • 别名
    MDG1;UNQ743/PRO1471
  • 类别
    抗体产品
  • 基因名称
    DNAJB9
  • 蛋白名称
    DnaJ homolog subfamily B member 9 (Microvascular endothelial differentiation gene 1 protein) (Mdg-1)
  • Clonality
    Polyclonal
  • 推荐应用
    WB
  • 稀释度
    WB 1:500-2000
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 制备方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    4189
  • Human Swissprot No.
    Q9UBS3
  • Mouse Gene ID
    27362
  • Mouse Swissprot No.
    Q9QYI6
  • Rat Gene ID
    24908
  • Rat Swissprot No.
    P97554
  • 特异性
    This antibody detects endogenous levels of DNAJB9 at Human, Mouse,Rat
  • 预测分子量
    25kDa
  • 组织表达
    Widely expressed. Expressed at highest level in the liver, placenta and kidney (PubMed:11836248).
  • 细胞定位
    Endoplasmic reticulum lumen .
  • 功能
    Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins . In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similarity). Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production (By similarity).
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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