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抗体蛋白
二抗生物素标记 过氧化物酶(HRP)标记 胶体金试剂 FITC荧光标记 RBITC荧光标记 二抗免疫血清 其它荧光标记二抗 藻红蛋白(PE)荧光标记 胶体金(Gold)标记 SAlexa Fluor荧光系列 碱性磷酸酶(AP)标记 别藻蓝蛋白(APC)荧光标记 其它标记 PE标记二抗 DyLight标记二抗 AU标记二抗 Biotin标记二抗 AMCA标记二抗 Texas Red标记二抗 TRITC标记二抗 HRP标记二抗 未标记二抗 Cy标记二抗 AbBox Fluor标记二抗内参抗体 小分子抗体抗体标记试剂盒细菌抗体蛋白病毒包装试剂杂交瘤融合筛选WB、IHC、ELISA相关试剂细胞培养试剂病原微生物抗原抗体假病毒抗体校准品其他抗原抗体标记的标签抗体病理级IHC抗体重组蛋白
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斑马鱼产品
订货方式
订货电话：13564444959
订货时间：周一至周五
订货Q Q：79688691
订货邮件：79688691@qq.com
订货时间：周一至周五
订货Q Q：79688691
订货邮件：79688691@qq.com
抗体类满2送1 产品简介
储存与保存
注意事项
产品简介-
产品名称CD43 Rabbit Polyclonal Antibody
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别名Leukosialin (Galactoglycoprotein;GALGP;Leukocyte sialoglycoprotein;Sialophorin;CD antigen CD43);CD43
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类别抗体产品
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基因名称SPN
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蛋白名称CD43
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ClonalityPolyclonal
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推荐应用WB,ELISA
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稀释度WB 1:1000-2000, ELISA 1:5000-20000
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反应种属Human,Rat,Mouse
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浓度1 mg/ml
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存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
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Human Gene ID6693
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Human Swissprot No.P16150
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Mouse Gene ID20737
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Mouse Swissprot No.P15702
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Rat Swissprot No.P13838
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免疫原Synthesized peptide derived from human CD43 AA range: 1-80
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特异性This antibody detects endogenous levels of Human CD43
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参考分子量44kDa
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宿主Rabbit
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同种型Rabbit,IgG
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背景介绍The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011],
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组织表达Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
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细胞定位Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Cell projection, uropodium . Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN). .; [CD43 cytoplasmic tail]: Nucleus . Nucleus, PML body . The sumoylated form localizes to the PML body. .
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功能disease:CD43 expression is defective on the T-cells of males with the immunodeficiency Wiskott-Aldrich syndrome. Affected males are susceptible to opportunistic infections and do not respond to polysaccharide antigens, reflecting defects in cytotoxic and helper T-cell functions.,function:One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.,PTM:Glycosylated; has a high content of sialic acid and O-linked carbohydrate structures.,subunit:Interacts with HIPK2 via the cytoplasmic domain.,tissue specificity:Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.,
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纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存1.保存：-20℃，Avoid freeze/thaw cycles
2.有效期：1年
注意事项1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
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