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p300 (12P7) Rabbit Monoclonal Antibody  Cite:0    分享
抗体类满2送1  

货号： IM35111
复制产品信息
  • 种属：H，M，R
  • 用途：WB，ELISA，IP，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
注意事项
储存与保存
产品简介
  • 产品名称
    p300 (12P7) Rabbit Monoclonal Antibody
  • 别名
    EP300;P300;Histone acetyltransferase p300;p300 HAT;E1A-associated protein p300
  • 类别
    抗体产品
  • 基因名称
    EP300
  • 蛋白名称
    Histone acetyltransferase p300
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IF-P,IF-F,IF-ICC,IP,ELISA
  • 稀释度
    WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200,
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    2033
  • Human Swissprot No.
    Q09472
  • Mouse Swissprot No.
    B2RWS6
  • 特异性
    Endogenous
  • 参考分子量
    300kDa
  • 预测分子量
    264kDa
  • 宿主
    Rabbit
  • 同种型
    IgG,Kappa
  • 背景介绍
    E1A binding protein p300(EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008],
  • 细胞定位
    Cytoplasm . Nucleus . Chromosome . Localizes to active chromatin: Colocalizes with histone H3 acetylated and/or crotonylated at 'Lys-18' (H3K18ac and H3K18cr, respectively) (PubMed:25818647). In the presence of ALX1 relocalizes from the cytoplasm to the nucleus. Colocalizes with ROCK2 in the nucleus (PubMed:12929931). .
  • 纯化
    Protein A
注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

备注：由于产品信息可能会有优化升级，请以实际收货标签信息为准。

储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

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