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Patched1 (Patched) (3G18) Mouse Monoclonal antibody  Cite:0    分享

货号: IM41225
复制产品信息
  • 种属:H,M,R
  • 用途:WB,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Patched1 (Patched) (3G18) Mouse Monoclonal antibody
  • 类别
    抗体产品
  • 基因名称
    PTCH1
  • Clonality
    Monoclonal
  • 推荐应用
    IF-P,IF-F,IF-ICC,WB
  • 稀释度
    WB 1:500, IF-P/IF-F/IF-ICC 1:100
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
  • Uniprot ID
    Q13635
  • Gene ID
    NM_000264
  • 免疫原
    Recombinant protein expressed in E.coli corresponding to amino acids 122-436 of human Patched1
  • 预测分子量
    160.4kDa
  • 宿主
    Mouse
  • 同种型
    IgG2b
  • 背景介绍
    This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
  • 纯化
    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
储存与保存

1.保存:-20℃,Avoid freeze/thaw cycles

2.有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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