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RASA1 (GAP ) (12M2) Mouse Monoclonal antibody  Cite:0    分享

货号： IM42787
复制产品信息
  • 种属：H，M，R
  • 用途：WB，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    RASA1 (GAP ) (12M2) Mouse Monoclonal antibody
  • 类别
    抗体产品
  • 基因名称
    RASA1
  • Clonality
    Monoclonal
  • 推荐应用
    IF-P,IF-F,IF-ICC,WB
  • 稀释度
    WB 1:2000, IF-P/IF-F/IF-ICC 1:100
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
  • Uniprot ID
    P20936
  • Gene ID
    NM_002890
  • 免疫原
    Full length human recombinant rotein of human RASA1(NP_002881) produced in HEK293T cell.
  • 预测分子量
    116.2kDa
  • 宿主
    Mouse
  • 同种型
    IgG1
  • 背景介绍
    The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues. [provided by RefSeq, May 2012]
  • 纯化
    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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