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HO-1 (Mix-mA) Mouse Monoclonal Antibody  Cite:0    分享

货号： IM47103
复制产品信息
  • 种属：H，M，R
  • 用途：WB，IHC-P，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    HO-1 (Mix-mA) Mouse Monoclonal Antibody
  • 别名
    Heme oxygenase 1 (HO-1) (EC 1.14.99.3);HO;HO1
  • 类别
    抗体产品
  • 基因名称
    HMOX1
  • 蛋白名称
    HO-1
  • Clonality
    Monoclonal
  • 推荐应用
    IHC-P,WB,IF-P,IF-F,IF-ICC
  • 稀释度
    IF-P/IF-F/IF-ICC 1:50-200, IHC-P 1:50-200, WB 1:1000-2000
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    3162
  • Human Swissprot No.
    P09601
  • Mouse Gene ID
    15368
  • Mouse Swissprot No.
    P14901
  • Rat Gene ID
    24451
  • Rat Swissprot No.
    P06762
  • 免疫原
    Synthesized peptide derived from human HO-1
  • 特异性
    This antibody detects endogenous levels of HO-1 at Human, Mouse,Rat
  • 预测分子量
    28kDa
  • 宿主
    Mouse
  • 背景介绍
    heme oxygenase 1(HMOX1) Homo sapiens Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008],
  • 组织表达
    Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level).
  • 细胞定位
    Endoplasmic reticulum membrane ; Single-pass type IV membrane protein ; Cytoplasmic side .
  • 功能
    catalytic activity:Heme + 3 AH(2) + 3 O(2) = biliverdin + Fe(2+) + CO + 3 A + 3 H(2)O.,function:Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.,induction:Heme oxygenase 1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA.,similarity:Belongs to the heme oxygenase family.,
  • 纯化
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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