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Acetyl Lysine(10B10)Mouse Monoclonal Antibody  Cite:0    分享

货号： IM47776
复制产品信息
  • 种属：Species independent
  • 用途：WB，IP，IHC-P，IF-P，IF-F
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Acetyl Lysine(10B10)Mouse Monoclonal Antibody
  • 类别
    抗体产品
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC IP
  • 稀释度
    WB 1:1000-2000, IHC-P 1:200-500, IP 1:100-200, IF-P/IF-F/IF-ICC 1:50-200
  • 反应种属
    Species independent
  • 存储缓冲液
    PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.
  • 免疫原
    Purified Protein
  • 特异性
    The antibody detects endogenous Acetyl Lysine protein.
  • 宿主
    Mouse
  • 背景介绍
    Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis. Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport. The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases , and HDACs have become promising targets for anti-cancer drugs currently in development.
  • 纯化
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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