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PLCB4 Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM49571
复制产品信息
  • 种属:H,R
  • 用途:WB,ELISA
规格:
50μl 100μl
单位:
支
单价:¥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    PLCB4 Rabbit Polyclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    PLCB4
  • 蛋白名称
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)
  • Clonality
    Polyclonal
  • 推荐应用
    WB,ELISA
  • 稀释度
    WB 1:500-2000, ELISA 1:5000-20000
  • 反应种属
    Human,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
  • Human Gene ID
    5332
  • Human Swissprot No.
    Q15147
  • Rat Swissprot No.
    Q9QW07
  • 免疫原
    Synthesized peptide derived from part region of human protein
  • 特异性
    PLCB4 Polyclonal Antibody detects endogenous levels of protein.
  • 预测分子量
    129kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010],
  • 组织表达
    Preferentially expressed in the retina.
  • 细胞定位
    intracellular,nucleus,smooth endoplasmic reticulum,cytosol,postsynaptic density,dendrite,
  • 信号通路
    Inositol phosphate metabolism;Calcium;Chemokine;Phosphatidylinositol signaling system;Vascular smooth muscle contraction;WNT;WNT-T CELLGap junction;Long-term potentiation;Long-term depression;GnRH;Melanogenesis;Alzheimer's disease;Huntington's disease;
  • 功能
    alternative products:Additional isoforms seem to exist,catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,tissue specificity:Preferentially expressed in the retina.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存:-20℃,Avoid freeze/thaw cycles

2.有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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