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E2F8 Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM49600
复制产品信息
  • 种属:H,M,R
  • 用途:WB,IF,FCM,IHC-P,IHC-F
规格:
50μl 100μl
单位:
支
单价:¥1416.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM49600
  • 产品名称
    E2F8 Rabbit Polyclonal Antibody
  • 别名
    E2F 8; E2F family member 82; E2F transcription factor 8; E2F-8; E2f8; E2F8_HUMAN; FLJ23311; Transcription factor E2F8.
  • 抗体来源
    Rabbit
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF,IHC-F,IF-ICC,FCM
  • 反应种属
    Human,Mouse,Rat (predicted: Rabbit,Pig,Chicken,Horse)
  • 理论分子量
    94 kDa
  • 细胞定位
    细胞核
  • 性状
    Liquid
  • 浓度
    1mg/ml
  • 免疫原
    KLH conjugated synthetic peptide derived from human E2F8: 265-360/968
  • 亚型
    IgG
  • 缓冲液
    0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
  • 背景介绍
    This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012].
  • 功能
    Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
  • 细胞表达
    Forms heterodimers with E2F7 and, to a lesser extent, homodimers. Dimerization is important for DNA binding.
  • 纯化
    affinity purified by Protein A
  • 稀释度
    WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,FCM=1ug/Test
储存与保存

1.保存:-20℃
2.有效期:1年

注意事项

1.我司生产的生化试剂如无特殊标注,基本为非无菌包装,若用于细胞实验,请提前做好预处理。需低温保存的产品,一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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