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IL-18 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM49697
复制产品信息
  • 种属：H，M，R
  • 用途：WB，ELISA，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    IL-18 Rabbit Polyclonal Antibody
  • 别名
    IGIF;IL1F4
  • 类别
    抗体产品
  • 基因名称
    IL18
  • 蛋白名称
    Interleukin-18 (IL-18) (Iboctadekin) (Interferon gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma)
  • Clonality
    Polyclonal
  • 推荐应用
    WB IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-2000, IF-P/IF-F/IF-ICC 1:100-300, ELISA 1:5000-20000, Not yet tested in other applications.
  • 反应种属
    Human,Rat,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
  • Human Gene ID
    3606
  • Human Swissprot No.
    Q14116
  • Mouse Swissprot No.
    P70380
  • Rat Swissprot No.
    P97636
  • 免疫原
    Synthesized peptide derived from part region of human protein
  • 特异性
    IL18 Polyclonal Antibody detects endogenous levels of protein.
  • 预测分子量
    21kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011],
  • 组织表达
    Liver,Peripheral blood,Urinary bladder,
  • 细胞定位
    Cytoplasm . Secreted . The precursor is cytosolic (PubMed:33883744). In response to inflammasome-activating signals, cleaved and secreted (PubMed:33883744). Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore (PubMed:33883744). In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation (PubMed:33883744). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10 (PubMed:32272059). .
  • 信号通路
    Cytokine-cytokine receptor interaction;NOD-like receptor;Cytosolic DNA-sensing pathway;
  • 功能
    function:Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.,online information:Interleukin-1 entry,similarity:Belongs to the IL-1 family.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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