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OCLN Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM50610
复制产品信息
  • 种属：H，M，R
  • 用途：ELISA，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    OCLN Rabbit Polyclonal Antibody
  • 别名
    OCLN; Occludin
  • 类别
    抗体产品
  • 基因名称
    OCLN
  • 蛋白名称
    Occludin;OCN
  • Clonality
    Polyclonal
  • 推荐应用
    WB IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-2000, IF-P/IF-F/IF-ICC 1:100-300, ELISA 1:5000-20000, Not yet tested in other applications.
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
  • Human Gene ID
    100506658
  • Human Swissprot No.
    Q16625
  • Mouse Swissprot No.
    Q61146
  • Rat Swissprot No.
    Q6P6T5
  • 免疫原
    Synthesized peptide derived from part region of human protein. AA350-400
  • 特异性
    OCLN Polyclonal Antibody detects endogenous levels of protein.
  • 预测分子量
    57kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],
  • 组织表达
    Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.
  • 细胞定位
    Cell membrane ; Multi-pass membrane protein . Cell junction, tight junction .
  • 信号通路
    Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;
  • 功能
    protein complex assembly, cellular amino acid derivative metabolic process, sulfur metabolic process, nucleoside metabolic process, ribonucleoside metabolic process, purine nucleoside metabolic process, macromolecular complex subunit organization, purine ribonucleoside metabolic process, S-adenosylhomocysteine metabolic process, S-adenosylmethionine metabolic process, macromolecular complex assembly, protein complex biogenesis,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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