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METTL11A Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM68018
复制产品信息
  • 种属:H,M,R
  • 用途:WB
规格:
50μl 100μl
单位:
支
单价:¥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    METTL11A Rabbit Polyclonal Antibody
  • 别名
    C9orf32;METTL11A;NRMT;AD-003
  • 类别
    抗体产品
  • 基因名称
    NTMT1
  • 蛋白名称
    N-terminal Xaa-Pro-Lys N-methyltransferase 1 (EC 2.1.1.244) (Alpha N-terminal protein methyltransferase 1A) (Methyltransferase-like protein 11A) (N-terminal RCC1 methyltransferase) (X-Pro-Lys N-terminal protein methyltransferase 1A) (NTM1A)
  • Clonality
    Polyclonal
  • 推荐应用
    WB
  • 稀释度
    WB 1:500-2000
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 制备方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    28989
  • Human Swissprot No.
    Q9BV86
  • Mouse Gene ID
    66617
  • Mouse Swissprot No.
    Q8R2U4
  • Rat Gene ID
    362103
  • Rat Swissprot No.
    Q5BJX0
  • 特异性
    This antibody detects endogenous levels of METTL11A at Human, Mouse,Rat
  • 预测分子量
    25kDa
  • 细胞定位
    Nucleus . Predominantly nuclear (PubMed:24090352).
  • 功能
    Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by NTMT2-mediated monomethylation . Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1). Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
储存与保存

1.保存:-20℃,Avoid freeze/thaw cycles

2.有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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