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TFEC Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM68259
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  • 种属:H,M,R
  • 用途:WB
规格:
50μl 100μl
单位:
支
单价:¥1100.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM68259
  • 产品名称
    TFEC Rabbit Polyclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    TFEC BHLHE34 TCFEC TFECL
  • 蛋白名称
    Transcription factor EC (TFE-C) (Class E basic helix-loop-helix protein 34) (bHLHe34) (Transcription factor EC-like) (hTFEC-L)
  • Clonality
    Polyclonal
  • 推荐应用
    WB
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 制备方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    22797
  • Human Swissprot No.
    O14948
  • Mouse Gene ID
    21426
  • Mouse Swissprot No.
    Q9WTW4
  • Rat Gene ID
    26296
  • Rat Swissprot No.
    Q63302
  • 特异性
    This antibody detects endogenous levels of TFEC at Human, Mouse,Rat
  • 稀释度
    WB 1:500-2000
  • 预测分子量
    38kDa
  • 组织表达
    Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
  • 细胞定位
    Nucleus .
  • 功能
    Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form.
储存与保存

-15°C to -25°C/1 year(Do not lower than -25°C)

注意事项

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

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