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eIF2α (Phospho Ser51) (16X3) Rabbit Monoclonal Antibody  Cite:0    分享
抗体类满2送1  

货号: IM50865
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 货号
    IM50865
  • 别名
    EIF2S1;EIF2A;Eukaryotic translation initiation factor 2 subunit 1;Eukaryotic translation initiation factor 2 subunit alpha;eIF-2-alpha;eIF-2A;eIF-2alpha
  • 产品名称
    eIF2α (Phospho Ser51) (16X3) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    EIF2S1
  • 蛋白名称
    Eukaryotic translation initiation factor 2 subunit 1
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    1965
  • Human Swissprot No.
    P05198
  • Mouse Gene ID
    13665
  • Mouse Swissprot No.
    Q6ZWX6
  • Rat Gene ID
    54318
  • Rat Swissprot No.
    P68101
  • 特异性
    eIF2α (Phospho Ser51) Monoclonal Antibody detects endogenous levels of eIF2α protein only when phosphorylated at S51.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ELsRR
  • 稀释度
    IHC-P 1:100-1:1000, WB 1:2000-1:10000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000
  • 参考分子链
    36kDa
  • 预测分子量
    36kDa
  • 宿主
    Rabbit
  • 同种型
    IgG,Kappa
  • 背景介绍
    The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],
  • 细胞定位
    Cytoplasm, Stress granule . Colocalizes with NANOS3 in the stress granules. .
  • 纯化
    Protein A
储存与保存

1.保存:-20℃
2.有效期:1年

注意事项

1.我司生产的生化试剂如无特殊标注,基本为非无菌包装,若用于细胞实验,请提前做好预处理。需低温保存的产品,一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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