热搜词： 生化试剂 血清抗 细胞 pvdf膜 抗体

咨询热线

13564444959

产品中心

当前位置：首页 > 产品中心 > 抗体蛋白 > 一抗
产品中心
订货方式
订货电话：13564444959
订货时间：周一至周五
订货Q Q：79688691
订货邮件：79688691@qq.com
Beclin-1 (Phospho Ser15) Rabbit Polyclonal Antibody  Cite:0    分享
抗体类满2送1  

货号： IM59429
复制产品信息
  • 种属：H，M
  • 用途：WB
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Beclin-1 (Phospho Ser15) Rabbit Polyclonal Antibody
  • 别名
    Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197);GT197
  • 类别
    抗体产品
  • 基因名称
    BECN1
  • 蛋白名称
    Beclin-1 (Ser15)
  • Clonality
    Polyclonal
  • 推荐应用
    WB
  • 反应种属
    Human,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    8678
  • Human Swissprot No.
    Q14457
  • Mouse Gene ID
    56208
  • Mouse Swissprot No.
    O88597
  • Rat Gene ID
    114558
  • Rat Swissprot No.
    Q91XJ1
  • 免疫原
    Synthesized phosho peptide around human Beclin-1 (Ser15)
  • 特异性
    This antibody detects endogenous levels of Human Mouse Beclin-1 (phospho-Ser15)
  • 稀释度
    WB 1:1000-2000
  • 预测分子量
    60kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
  • 组织表达
    Ubiquitous.
  • 细胞定位
    Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .
  • 信号通路
    Regulation of autophagy;
  • 功能
    function:Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.,similarity:Belongs to the beclin family.,subcellular location:Expressed in dendrites and cell bodies of cerebellar Purkinje cells.,subunit:Interacts with GOPC and GRID2. Interacts with AMBRA1. Probably forms a complex with AMBRA1 and PIK3C3 (By similarity). Interacts with BCL2 and BCL2L1.,tissue specificity:Ubiquitous.,
  • 纯化
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存与保存

1. 保存：-20℃，Avoid freeze/thaw cycles
2. 有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

备注：由于产品信息可能会有优化升级，请以实际收货标签信息为准。

产品推荐
<