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PI3 Kinase Class III (Phospho Ser249) Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM59572
复制产品信息
  • 种属：H，M，R
  • 用途：WB，ELISA，IHC-P
规格:
50μl 100μl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    PI3 Kinase Class III (Phospho Ser249) Rabbit Polyclonal Antibod
  • 别名
    Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34);VPS34
  • 类别
    抗体产品
  • 基因名称
    PIK3C3
  • 蛋白名称
    PI3 Kinase Class III (Ser249)
  • Clonality
    Polyclonal
  • 推荐应用
    WB,ELISA,IHC-P
  • 稀释度
    WB 1:500-2000, IHC-P 1:50-300, ELISA 2000-20000
  • 反应种属
    Human,Rat,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    5289
  • Human Swissprot No.
    Q8NEB9
  • Mouse Gene ID
    225326
  • Mouse Swissprot No.
    Q6PF93
  • Rat Gene ID
    65052
  • Rat Swissprot No.
    O88763
  • 免疫原
    Synthesized phosho peptide around human PI3 Kinase Class III (Ser249)
  • 特异性
    This antibody detects endogenous levels of Human PI3 Kinase Class III (phospho-Ser249)
  • 预测分子量
    100kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 组织表达
    Ubiquitously expressed, with a highest expression in skeletal muscle.
  • 细胞定位
    Midbody . Late endosome . Cytoplasmic vesicle, autophagosome . As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (PubMed:14617358). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity). .
  • 信号通路
    Inositol phosphate metabolism;Phosphatidylinositol signaling system;Regulation of autophagy;
  • 功能
    catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.,cofactor:Manganese.,function:Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4.,tissue specificity:Ubiquitously expressed, with a highest expression in skeletal muscle.,
  • 纯化
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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