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Adenosine A2A-R Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM52138
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  • 种属：H，M，R
  • 用途：WB，ELISA，IHC-P，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Adenosine A2A-R Rabbit Polyclonal Antibody
  • 别名
    ADORA2A; ADORA2; Adenosine receptor A2a
  • 类别
    抗体产品
  • 基因名称
    ADORA2A
  • 蛋白名称
    Adenosine receptor A2a
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-1:2000, IHC-P 1:100-1:300, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000.Not yet tested in other applications.
  • 反应种属
    Human,Rat,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    135
  • Human Swissprot No.
    P29274
  • Mouse Swissprot No.
    Q60613
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human ADORA2A. AA range:120-169
  • 特异性
    Adenosine A2A-R Polyclonal Antibody detects endogenous levels of Adenosine A2A-R protein.
  • 预测分子量
    37kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    adenosine A2a receptor(ADORA2A) Homo sapiens This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript compos
  • 组织表达
    Brain,Hippocampus,Lymph,Thymus
  • 细胞定位
    Cell membrane ; Multi-pass membrane protein . Colocalizes with GAS2L2 at neuronal processes.
  • 信号通路
    Calcium;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction
  • 功能
    function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年


注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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