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Adenosine A3-R Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM52139
复制产品信息
  • 种属：H，M，R
  • 用途：WB，ELISA，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Adenosine A3-R Rabbit Polyclonal Antibody
  • 别名
    ADORA3; Adenosine receptor A3
  • 类别
    抗体产品
  • 基因名称
    ADORA3
  • 蛋白名称
    Adenosine receptor A3
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-1:2000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:10000.Not yet tested in other applications.
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    140
  • Human Swissprot No.
    P33765
  • Mouse Swissprot No.
    Q61618
  • Rat Gene ID
    1.00912e+008
  • Rat Swissprot No.
    P28647
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human ADORA3. AA range:255-304
  • 特异性
    Adenosine A3-R Polyclonal Antibody detects endogenous levels of Adenosine A3-R protein.
  • 预测分子量
    36kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014],
  • 组织表达
    Adrenal gland,Brain,Heart,Lung,Testis
  • 细胞定位
    plasma membrane,integral component of membrane
  • 信号通路
    Neuroactive ligand-receptor interaction
  • 功能
    function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.,PTM:Phosphorylation on Ser-317 may be crucial for rapid desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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