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Annexin VI Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM52226
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  • 种属：H，M，R
  • 用途：WB，ELISA，IHC-P，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Annexin VI Rabbit Polyclonal Antibody
  • 别名
    ANXA6; ANX6; Annexin A6; 67 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70
  • 类别
    抗体产品
  • 基因名称
    ANXA6
  • 蛋白名称
    Annexin A6
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-1:2000, IHC-P 1:100-300, ELISA 1:20000, IF-P/IF-F/IF-ICC 1:100-300, Not yet tested in other applications.
  • 反应种属
    Human,Rat,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    309
  • Human Swissprot No.
    P08133
  • Mouse Swissprot No.
    P14824
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human Annexin A6. AA range:1-50
  • 特异性
    Annexin VI Polyclonal Antibody detects endogenous levels of Annexin VI protein.
  • 预测分子量
    75kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010],
  • 组织表达
    Adipocyte,Amygdala,Lung,Uterus,
  • 细胞定位
    Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • 功能
    caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.,induction:By EBV.,miscellaneous:Seems to bind one calcium ion with high affinity.,PTM:Phosphorylated in response to growth factor stimulation.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,similarity:Contains 8 annexin repeats.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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