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Calnexin Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM52553
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IHC-P,IF-P,IF-F,IF-ICC
规格:
20μl 50μl 100μl
单位:
支
单价:¥800.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM52553
  • 别名
    CANX; Calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90
  • 产品名称
    Calnexin Rabbit Polyclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    CANX
  • 蛋白名称
    Calnexin
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    821
  • Human Swissprot No.
    P27824
  • Mouse Gene ID
    12330
  • Mouse Swissprot No.
    P35564
  • Rat Gene ID
    29144
  • Rat Swissprot No.
    P35565
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human Calnexin. AA range:543-592
  • 特异性
    Calnexin Polyclonal Antibody detects endogenous levels of Calnexin protein
  • 稀释度
    WB 1:500-1:2000, IHC-P 1:100-300, ELISA 1:20000, IF-P/IF-F/IF-ICC 1:100-300, Not yet tested in other applications.
  • 预测分子量
    90kDa
  • 运输及保存条件
    -20°C/1 year
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
  • 组织表达
    B-cell lymphoma,Epithelium,Fibroblast,Keratinocyte,Kidney,Liver,Lymph,Placenta,Platelet
  • 细胞定位
    Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232).
  • 信号通路
    Antigen processing and presentation;
  • 功能
    function:Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.,online information:Calnexin entry,similarity:Belongs to the calreticulin family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存:-20℃

2.有效期:1年

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