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Glucagon Receptor Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM53651
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  • 种属：H，M，R
  • 用途：WB，ELISA，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Glucagon Receptor Rabbit Polyclonal Antibody
  • 别名
    GCGR; Glucagon receptor; GL-R
  • 类别
    抗体产品
  • 基因名称
    GCGR
  • 蛋白名称
    Glucagon receptor
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-1:2000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000.Not yet tested in other applications.
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    2642
  • Human Swissprot No.
    P47871
  • Mouse Gene ID
    14527
  • Mouse Swissprot No.
    Q61606
  • Rat Gene ID
    24953
  • Rat Swissprot No.
    P30082
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human GLR. AA range:95-144
  • 特异性
    Glucagon Receptor Polyclonal Antibody detects endogenous levels of Glucagon Receptor protein.
  • 预测分子量
    54kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    glucagon receptor(GCGR) Homo sapiens The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010],
  • 组织表达
    Liver,Placenta
  • 细胞定位
    Cell membrane ; Multi-pass membrane protein . Is rapidly internalized after ligand-binding.
  • 信号通路
    Neuroactive ligand-receptor interaction
  • 功能
    disease:It is a candidate for certain defects in non-insulin-dependent diabetes mellitus (NIDDM). The variant in position 40 (Ser) is found in some NIDDM patients, but also in nondiabetic subjects.,function:This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 2 family.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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