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N-cadherin Rabbit Polyclonal Antibody  Cite:0    分享

货号: IM54530
复制产品信息
  • 种属:H,M,R
  • 用途:WB,ELISA,IHC-P,IF-P,IF-F,IF-ICC
规格:
50μl 100μl
单位:
单价:¥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    N-cadherin Rabbit Polyclonal Antibody
  • 别名
    CDH2; CDHN; NCAD; Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD antigen CD325
  • 类别
    抗体产品
  • 基因名称
    CDH2
  • 蛋白名称
    Cadherin-2
  • Clonality
    Polyclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    WB 1:500-1:2000, IHC-P 1:100-1:300, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:10000.Not yet tested in other applications.
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    1000
  • Human Swissprot No.
    P19022
  • Mouse Gene ID
    12558
  • Mouse Swissprot No.
    P15116
  • Rat Gene ID
    83501
  • Rat Swissprot No.
    Q9Z1Y3
  • 免疫原
    The antiserum was produced against synthesized peptide derived from human CDH2. AA range:721-770
  • 特异性
    N-cadherin Polyclonal Antibody detects endogenous levels of N-cadherin protein.
  • 预测分子量
    140kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015],
  • 组织表达
    Brain,Epithelium,Liver,
  • 细胞定位
    Cell membrane ; Single-pass type I membrane protein . Cell membrane, sarcolemma . Cell junction . Cell surface . Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes. .
  • 信号通路
    Cell adhesion molecules (CAMs);Arrhythmogenic right ventricular cardiomyopathy (ARVC);
  • 功能
    function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存:-20℃,Avoid freeze/thaw cycles

2.有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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