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Integrin α1 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM57187
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  • 种属：H，M，R
  • 用途：ELISA，IHC-P，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Integrin α1 Rabbit Polyclonal Antibody
  • 别名
    Integrin alpha-1 (CD49 antigen-like family member A;Laminin and collagen receptor;VLA-1;CD antigen CD49a)
  • 类别
    抗体产品
  • 基因名称
    ITGA1
  • 蛋白名称
    Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a)
  • Clonality
    Polyclonal
  • 推荐应用
    IHC-P,IF-P,IF-F,IF-ICC,ELISA
  • 稀释度
    IHC-P 1:50-200, ELISA 1:10000-20000, IF-P/IF-F/IF-ICC 1:50-200
  • 反应种属
    Human,Rat,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    3672
  • Human Swissprot No.
    P56199
  • Mouse Gene ID
    109700
  • Mouse Swissprot No.
    Q3V3R4
  • 免疫原
    Synthetic peptide from human protein at AA range: 920-980
  • 特异性
    The antibody detects endogenous Integrin α1
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    integrin subunit alpha 1(ITGA1) Homo sapiens This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008],
  • 组织表达
    Brain,Liver,Plasma,
  • 细胞定位
    Membrane; Single-pass type I membrane protein.
  • 信号通路
    Focal adhesion;ECM-receptor interaction;Hematopoietic cell lineage;Regulates Actin and Cytoskeleton;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;
  • 功能
    domain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,function:Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1. Interacts with RAB21.
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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