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CACB1 Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM58310
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  • 种属：H，M，R
  • 用途：WB
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    CACB1 Rabbit Polyclonal Antibody
  • 别名
    CACNLB1
  • 类别
    抗体产品
  • 基因名称
    CACNB1
  • 蛋白名称
    CACB1
  • Clonality
    Polyclonal
  • 推荐应用
    WB
  • 稀释度
    WB 1:500-2000
  • 反应种属
    Human,Mouse,Rat
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    782
  • Human Swissprot No.
    Q02641
  • Mouse Gene ID
    12295
  • Mouse Swissprot No.
    Q8R3Z5
  • Rat Gene ID
    50688
  • Rat Swissprot No.
    P54283
  • 免疫原
    Synthesized peptide derived from human CACB1 AA range: 79-129
  • 特异性
    This antibody detects endogenous levels of CACB1 at Human/Mouse/Rat
  • 参考分子量
    66kDa
  • 同种型
    Rabbit,IgG
  • 背景介绍
    The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
  • 组织表达
    Detected in heart ventricle (at protein level) (PubMed:15615847). Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.
  • 细胞定位
    Cell membrane, sarcolemma ; Peripheral membrane protein ; Cytoplasmic side . Cell membrane ; Peripheral membrane protein .
  • 功能
    function:The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.,similarity:Belongs to the calcium channel beta subunit family.,similarity:Contains 1 SH3 domain.,subunit:The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with JSRP1.,tissue specificity:Expressed in brain, heart and spleen (isoform 1 and 3) and in skeletal muscle (isoform 2).,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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