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LC3A Rabbit Polyclonal Antibody  Cite:0    分享

货号： IM62929
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  • 种属：H，M，R
  • 用途：WB，ELISA，IHC-P
规格:
50μl 100μl
单位:
支
单价:￥1500.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    LC3A Rabbit Polyclonal Antibody
  • 别名
    Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;MAP1 light chain 3-like protein 1;MAP1A/MAP1B light chain 3 A;MAP1A/MAP1B LC3 A;Microtubule-associated protein 1 light chain 3 alpha)
  • 类别
    抗体产品
  • 基因名称
    MAP1LC3A
  • 蛋白名称
    LC3A
  • Clonality
    Polyclonal
  • 推荐应用
    WB,ELISA,IHC-P
  • 稀释度
    WB 1:500-2000, IHC-P 1:50-300, ELISA 2000-20000
  • 反应种属
    Human,Rat,Mouse
  • 浓度
    1 mg/ml
  • 存储缓冲液
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
  • Human Gene ID
    84557
  • Human Swissprot No.
    Q9H492
  • Mouse Gene ID
    66734
  • Mouse Swissprot No.
    Q91VR7
  • Rat Gene ID
    362245
  • Rat Swissprot No.
    Q6XVN8
  • 免疫原
    Synthesized peptide derived from human LC3A
  • 特异性
    This antibody detects endogenous levels of Human LC3A
  • 参考分子量
    13kDa
  • 宿主
    Rabbit
  • 同种型
    Rabbit,IgG
  • 背景介绍
    function:Probably involved in formation of autophagosomal vacuoles (autophagosomes).,PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:LC3-II binds to the autophagic membranes.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.,tissue specificity:Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,
  • 组织表达
    Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
  • 细胞定位
    Cytoplasmic vesicle, autophagosome membrane ; Lipid-anchor . Endomembrane system ; Lipid-anchor . Cytoplasm, cytoskeleton . LC3-II binds to the autophagic membranes. .
  • 功能
    autophagic vacuole formation, proteolysis, autophagy, vacuole organization, macromolecule catabolic process, cellular response to starvation, response to extracellular stimulus, macroautophagy, modification-dependent protein catabolic process, protein catabolic process, response to nutrient levels, cellular response to extracellular stimulus, cellular response to nutrient levels, cellular response to stress, response to starvation, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process,proteolysis involved in cellular protein catabolic process,
  • 纯化
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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