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HER2 (8L17) Rabbit Monoclonal Antibody  Cite:0    分享
抗体类满2送1  

货号: IM39097
复制产品信息
  • 种属:H
  • 用途:WB,IF-ICC
规格:
50µl 100µl
单位:
单价:¥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    HER2 (8L17) Rabbit Monoclonal Antibody
  • 别名
    NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu
  • 类别
    抗体产品
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IF-ICC
  • 稀释度
    WB 1:1000, IF-ICC 1:50
  • 反应种属
    Human
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Uniprot ID
    P04626
  • Gene ID
    2064
  • 免疫原
    A synthetic peptide of human HER2
  • 参考分子量
    185kDa
  • 预测分子量
    138kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 背景介绍
    This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
  • 纯化
    Affinity Purification
储存与保存

1. 保存:-20℃,Avoid freeze/thaw cycles

2. 有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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