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RAP1GAP (4X12) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM39576
复制产品信息
  • 种属：H，M，R
  • 用途：WB，FCM，IP，IF-ICC
规格:
50µl 100µl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    RAP1GAP (4X12) Rabbit Monoclonal Antibody
  • 别名
    RAPGAP; RAP1GA1; RAP1GAP1; RAP1GAPII
  • 类别
    抗体产品
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IF-ICC,FCM,IP
  • 稀释度
    WB 1:1000-1:5000, IF-ICC 1:20-1:50, FCM 1:20, IP 1:20
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Uniprot ID
    P47736
  • Gene ID
    5909
  • 免疫原
    A synthetic peptide of human RAP1GAP
  • 参考分子量
    95kDa
  • 预测分子量
    73kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 背景介绍
    This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011]
  • 纯化
    Affinity Purification
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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