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Creatine kinase B type (12W4) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM35815
复制产品信息
  • 种属：H，M，R
  • 用途：WB，FCM，IHC-P，IF-P，IF-ICC
规格:
50µl 100µl
单位:
支
单价:￥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    Creatine kinase B type (12W4) Rabbit Monoclonal Antibody
  • 别名
    BCK; Ckb; CKBB; HEL 211; HEL S 29
  • 类别
    抗体产品
  • 基因名称
    CKB
  • 蛋白名称
    CKBB
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-ICC,FCM
  • 稀释度
    WB 1:2000-1:20000, IHC-P/IF-P 1:100-1:1000, IF-ICC 1:50-1:500, FCM 1:10-1:100
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID
    1152
  • Human Swissprot No.
    P12277
  • 免疫原
    A synthetic peptide of human Creatine kinase B type
  • 参考分子量
    43kDa
  • 预测分子量
    43kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 细胞定位
    Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q04447}. Mitochondrion {ECO:0000250|UniProtKB:Q04447}. Note=Localizes to the mitochondria of thermogenic fat cells via the internal MTS-like signal (iMTS-L) region {ECO:0000250|UniProtKB:Q04447}
  • 功能
    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) (PubMed:8186255). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation (By similarity). During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N- phosphocreatine as heat without performing any mechanical or chemical work (By similarity).
  • 纯化
    Affinity-chromatography
储存与保存

1.保存：-20℃，Avoid freeze/thaw cycles

2.有效期：1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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