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PTBP1 (3J11) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM35962
复制产品信息
  • 种属:H,M,R
  • 用途:WB,FCM,IHC-P,IF-P,IF-ICC
规格:
50µl 100µl
单位:
支
单价:¥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品名称
    PTBP1 (3J11) Rabbit Monoclonal Antibody
  • 别名
    PTB; PTB2; PTB3; PTB4; pPTB; HNRPI; PTB-1; PTB-T; HNRNPI; HNRNP-I
  • 类别
    抗体产品
  • 基因名称
    PTBP1
  • 蛋白名称
    PTB
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-P,IF-ICC,FCM
  • 稀释度
    WB 1:2000-1:20000, IHC-P/IF-P 1:100-1:200, IF-ICC 1:200-1:500, FCM 1:200-1:2000
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID
    5725
  • Human Swissprot No.
    P26599
  • 免疫原
    A synthetic peptide of human PTBP1
  • 参考分子量
    57kDa
  • 预测分子量
    57kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 细胞定位
    Nucleus
  • 功能
    Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre- mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre- mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
  • 纯化
    Affinity-chromatography
储存与保存

1.保存:-20℃,Avoid freeze/thaw cycles

2.有效期:1年

注意事项

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

3. 实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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