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AS160 (Phospho T642) (11S14) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM37067
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  • 种属：H
  • 用途：WB
规格:
50µl 100µl
单位:
支
单价:￥1200.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM37067
  • 别名
    AS160; BUB2; CDC16; NIDDM5; Tbc1d4
  • 产品名称
    AS160 (Phospho T642) (11S14) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    TBC1D4
  • 蛋白名称
    AS160, KIAA0603
  • Clonality
    Monoclonal
  • 推荐应用
    WB
  • 反应种属
    Human
  • 存储缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Human Gene ID
    9882
  • Human Swissprot No.
    O60343
  • 稀释度
    WB 1:1000-1:2000
  • 参考分子量
    180kDa
  • 预测分子量
    147kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 注意事项
    Phospho-AS160 (T642) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 组织表达
    Widely expressed. Isoform 2 is the highest overexpressed in most tissues. Isoform 1 is highly expressed in skeletal muscle and heart, but was not detectable in the liver nor in adipose tissue. Isoform 2 is strongly expressed in adrenal and thyroid gland, and also in lung, kidney, colon, brain and adipose tissue Isoform 2 is moderately expressed in skeletal muscle. Expressed in pancreatic Langerhans islets, including beta cells (at protein level) Expression is decreased by twofold in pancreatic islets in type 2 diabetes patients compared to control subjects. Up-regulated in T-cells from patients with atopic dermatitis.
  • 细胞定位
    Cytoplasm. Note=Isoform 2 shows a cytoplasmic perinuclear localization in a myoblastic cell line in resting and insulin-stimulated cells
  • 功能
    May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.
  • 纯度
    Affinity-chromatography
储存与保存

Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles.

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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