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Bcl-XL (4B16) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM37097
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  • 种属:H,M,R
  • 用途:WB,FCM,IP,IHC-P,IF-P,IF-ICC
规格:
50µl 100µl
单位:
支
单价:¥1600.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM37097
  • 别名
    Apoptosis regulator Bcl-X; BLC2L; Bcl-2-like 1 protein bclxl; BCL2L; BCL2L1; BCLX
  • 产品名称
    Bcl-XL (4B16) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    BCL2L1
  • 蛋白名称
    BCL2L, BCLX
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IHC-P,IF-ICC,FCM,IP,IF-P
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID
    598
  • Human Swissprot No.
    Q07817
  • 免疫原
    A synthetic peptide of human Bcl-XL
  • 稀释度
    WB 1:1000, IHC-P/IF-P 1:200-1:2000, IF-ICC 1:100-1:500, FCM 1:20-1:100, IP 1:10-1:50
  • 参考分子量
    30kDa
  • 预测分子量
    26kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 注意事项
    Bcl-XL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 组织表达
    Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain
  • 细胞定位
    [Isoform Bcl-X(L)]: Mitochondrion inner membrane. Mitochondrion outer membrane Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. Note=After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner (By similarity). Localizes to the centrosome when phosphorylated at Ser-49
  • 功能
    Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(S) promotes apoptosis.
  • 纯度
    Affinity-chromatography
储存与保存

Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles.

注意事项

1.我司生产的生化试剂如无特殊标注,基本为非无菌包装,若用于细胞实验,请提前做好预处理。需低温保存的产品,一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。 

 

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