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BCAR1 (Phospho Y410) (17X7) Rabbit Monoclonal Antibody  Cite:0    分享

货号: IM37108
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  • 种属:H
  • 用途:WB
规格:
50µl 100µl
单位:
支
单价:¥1200.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM37108
  • 别名
    BCAR 1; Bcar1; Breast cancer anti estrogen resistance 1 Breast cancer anti-estrogen resistance protein 1; CAS; Cas scaffolding protein family member 1; CAS1; Cass1; Crk associated substrate; Crk associated substrate p130Cas; CRK-associated substrate; CRKAS; p130cas.
  • 产品名称
    BCAR1 (Phospho Y410) (17X7) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    BCAR1
  • 蛋白名称
    CAS, CASS1, CRKAS
  • Clonality
    Monoclonal
  • 推荐应用
    WB
  • 反应种属
    Human
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • Human Gene ID
    9564
  • Human Swissprot No.
    P56945
  • 免疫原
    A synthetic phosphopeptide corresponding to residues surrounding Tyr410 of human BCAR1
  • 稀释度
    WB 1:1000-1:5000
  • 参考分子量
    130kDa
  • 预测分子量
    93kDa
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 注意事项
    Phospho-BCAR1 (Y410) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
  • 组织表达
    Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line.
  • 细胞定位
    Cell junction, focal adhesion. Cytoplasm Cell projection, axon {ECO:0000250|UniProtKB:Q61140} Note=Unphosphorylated form localizes in the cytoplasm (By similarity) Localizes to focal adhesion sites following integrin engagement (By similarity). {ECO:0000250|UniProtKB:Q61140}.
  • 功能
    Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (PubMed:12832404, PubMed:12432078). Implicated in induction of cell migration and cell branching (PubMed:12432078, PubMed:12832404, PubMed:17038317). Involved in the BCAR3-mediated inhibition of TGFB signaling (By similarity).
  • 纯度
    Affinity-chromatography
储存与保存

Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles.

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1.我司生产的生化试剂如无特殊标注,基本为非无菌包装,若用于细胞实验,请提前做好预处理。需低温保存的产品,一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。 

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