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SMC1A (5F18) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM68663
复制产品信息
  • 种属：H，M，R
  • 用途：WB，IHC-P
规格:
50μl 100μl
单位:
支
单价:￥1200.00
产品简介
储存与保存
注意事项
产品简介
  • 产品货号
    IM68663
  • Uniprot ID
    Q14683
  • Gene ID
    8243
  • 别名
    SMC1; SMCB; CDLS2; SB1.8; SMC1L1; DXS423E; SMC1alpha
  • 产品名称
    SMC1A (5F18) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • Clonality
    Monoclonal
  • Monoclonal
    WB,IHC-P
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
  • 稀释度
    WB 1:2000-1:20000, IHC-P/IF-P 1:200-1:500
  • 参考分子量
    145kDa
  • 预测分子量
    143kDa
  • 性状
    Liquid
  • 宿主
    Rabbit
  • 同种型
    IgG
  • 背景介绍
    Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013].
  • 纯化
    Affinity Purification
储存与保存

Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles.

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。 

3.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。 

4.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。 

 

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