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PI3 Kinase p85 (Phospho Tyr458)/p55 (Phospho Tyr199) (5Y18) Rabbit Monoclonal Antibody  Cite:0    分享

货号： IM72052
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  • 种属：H，M，R
  • 用途：WB，ELISA，IF-P，IF-F，IF-ICC
规格:
50μl 100μl
单位:
支
单价:￥1300.00
产品简介
储存与保存
注意事项
产品简介
  • 货号
    IM72052
  • 别名
    PIK3R1;GRB1;Phosphatidylinositol 3-kinase regulatory subunit alpha;PI3-kinase regulatory subunit alpha;PI3K regulatory subunit alpha;PtdIns-3-kinase regulatory subunit alpha;Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;PI3-kinase subunit p85-alpha;PtdIns-3-kinase regulatory subunit p85-alpha;PIK3R2;Phosphatidylinositol 3-kinase regulatory subunit beta;PI3-kinase regulatory subunit beta;PI3K regulatory subunit beta;PtdIns-3-kinase regulatory subunit beta;
  • 产品名称
    PI3 Kinase p85 (Phospho Tyr458)/p55 (Phospho Tyr199) (5Y18) Rabbit Monoclonal Antibody
  • 类别
    抗体产品
  • 基因名称
    PIK3R1/PIK3R2/PIK3R3
  • 蛋白名称
    Phosphatidylinositol 3-kinase regulatory subunit alpha/beta/gamma
  • Clonality
    Monoclonal
  • 推荐应用
    WB,IF-P,IF-F,IF-ICC,ELISA
  • 反应种属
    Human,Mouse,Rat
  • 存储缓冲液
    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Human Gene ID
    5295
  • Human Swissprot No.
    P27986;Q92569;O00459
  • Mouse Gene ID
    18708;18709;18710
  • Mouse Swissprot No.
    O08908
  • Rat Gene ID
    25513;60664
  • Rat Swissprot No.
    Q63787;Q63788;Q63789
  • 特异性
    PI3 Kinase p85 (Phospho Tyr458)/p55 (Phospho Tyr199) detects endogenous levels of PI3 kinase p85/p55 only when phosphorylated at Human:Y467/Y199, Mouse:Y467/Y199, Rat:Y467/Y199..The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RLyEE
  • 稀释度
    WB 1:1000-1:5000, IF-P/IF-F/IF-ICC 1:200-1:1000, ELISA 1:5000-1:20000
  • 参考分子量
    85kDa,55kDa
  • 预测分子量
    85kDa,55kDa
  • 宿主
    Rabbit
  • 同种型
    IgG,Kappa
  • 背景介绍
    Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],
  • 组织表达
    Isoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level).
  • 细胞定位
    nucleus,cytoplasm,cis-Golgi network,cytosol,plasma membrane,cell-cell junction,phosphatidylinositol 3-kinase complex,phosphatidylinositol 3-kinase complex, class IA,membrane,perinuclear endoplasmic reticulum membrane,
  • 纯化
    Protein A
储存与保存

1.保存：-20℃
2.有效期：1年

注意事项

1.我司生产的生化试剂如无特殊标注，基本为非无菌包装，若用于细胞实验，请提前做好预处理。需低温保存的产品，一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。

2.本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。

3.为了您的安全和健康，请穿实验服并戴一次性手套操作。

4.实验结果受多种因素影响，相关处理仅限于产品本身，不涉及其他赔偿。

 

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